Field of Cancerization in Peripheral Airway Epithelium: Gene Expresssion

ABSTRACT: Field of cancerization in the airway epithelium has been increasing examined to understand early pathogenesis of non-small cell lung cancer. This study uses microarray high-throughput technologies to characterize the molecular aberrations in the terminal airway and bronchoalveolar cells in the context of field cancerization in high-risk smokers and lung cancer patients. We collected peripheral airway brushings from the contral-lateral lung of the tumor from cancer patients (n=17) and smoker controls (n=13); Total RNA were obtained from the peripheral airway epithelium.

ORGANISM(S): Homo sapiens

SUBMITTER: Tsay Jun-Chieh 

PROVIDER: S-ECPF-GEOD-54495 | biostudies-other |

REPOSITORIES: biostudies-other