Gene expression profiles of PDX models with acquired resistance to endocrine treatments

ABSTRACT: Acquired resistance to endocrine therapy occurs with high frequency in patients with luminal breast cancer (LBC). We report here the establishment of four patient-derived xenograft models of LBC with acquired resistance in vivo to tamoxifen and estrogen deprivation. CEL files represent expresison data generated from 5 replicates (independent mice) of the following tumor models: HBCx22 (parental), HBCx22 TamR (tamoxifen-resistant), HBCx22 OvaR (ovariectomy-resistant), HBCx34 (parental), HBCx34 TamR (tamoxifen-resistant), HBCx34 OvaR (ovariectomy-resistant)

ORGANISM(S): Homo sapiens

SUBMITTER: Cottu P 

PROVIDER: S-ECPF-GEOD-55561 | biostudies-other | 2014 Aug

REPOSITORIES: biostudies-other