Transcription profiling of human tumor and stroma from breast catured by LCM of inflammatory and non inflammatory breast cancers

ABSTRACT: Tumor epithelium and surrounding stromal cells were isolated using laser capture microdissection of human breast cancer to examine differences in gene expression based on tissue types from inflammatory and non-inflammatory breast cancer Experiment Overall Design: We applied LCM to obtain samples enriched in tumor epithelium and stroma from 15 IBC and 35 non-IBC cases to study the relative contribution of each component to the IBC phenotype and to patient survival.

ORGANISM(S): Homo sapiens

SUBMITTER: Boersma BJ 

PROVIDER: S-ECPF-GEOD-5847 | biostudies-other | 2008 Mar

REPOSITORIES: biostudies-other