RNA expression changes in MDA-MB-231 cells following MEK inhibition

ABSTRACT: Molecular responses to MEK inhibition in cancer cells are complex and dynamic. We performed a time-series experiment to measure global RNA expression changes following treatment with the MEK inihibor U0126 MDA-MB-231 human breast cancer cells were grown in low-serum conditions. Treatment with U0126 was initiated in the presence of EGF. RNA was harvested at multiple time points during the course of 48 hours.

ORGANISM(S): Homo sapiens

SUBMITTER: Korn Wolfgang 

PROVIDER: S-ECPF-GEOD-61364 | biostudies-other |

REPOSITORIES: biostudies-other