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Transcription profiling of human MDA-MB-231 cells infeted with Flag-SR-IkBa vs. vector

ABSTRACT: We used human Affymetrix microarrays to identify the up- or down-regulated gene expressions from MDA-MB-231 cells infected with control vector or Flag-SR-IkBa Experiment Overall Design: The pattern of gene expression from MDA-MB-231 cells transduced with retroviruses were analysed by RNA extraction and hybridization on Affymetrix microarrays. From expression profiles, we identified NF-kB target genes, and uncovered a novel and specific role of a gene in osteolytic bone metastasis.

ORGANISM(S): Homo sapiens

SUBMITTER: Park BK 

PROVIDER: S-ECPF-GEOD-6324 | biostudies-other | 2007 Jan

REPOSITORIES: biostudies-other

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