Transcription profiling of human Melanoma cell lines to investigate differences in wild-type p14ARF and mutant 14ARF

ABSTRACT: 35 Melanoma cell lines hybridized to Affymetrix Hu133_Plus 2 microarrays were analysed for genes differentially expressed between cell lines carrying wild-type p14ARF and those with mutant 14ARF. All of these cell lines contained wild-type p53 (so that the effects of p14ARF mutations could be analysed without contamination from p53). Experiment Overall Design: The aim of this study was to identify downstream effectors of p14ARF in melanoma. Relevant paper: Packer et al. (2007) Int J Cancer.

ORGANISM(S): Homo sapiens

SUBMITTER: Packer LM 

PROVIDER: S-ECPF-GEOD-7152 | biostudies-other | 2007 Aug

REPOSITORIES: biostudies-other