Transcription profiling by array of NCI-H460 cells grown as spheres or in adherent conditions

ABSTRACT: In this study, we provide evidence that spheroids cells isolated from established human NSCLC cell lines are highly enriched in NSCLC-TICs that aberrant Akt-IL6-Stat3 signalling axis is necessary for self-renewal of lung TICs in vitro and for tumor formation in vivo.

ORGANISM(S): Homo sapiens

SUBMITTER: Viglietto Giuseppe 

PROVIDER: S-ECPF-MTAB-1699 | biostudies-other |

REPOSITORIES: biostudies-other