Purification of an Arg-Gly-Asp selective matrix receptor from brain synaptic plasma membranes.

ABSTRACT: Brain synaptic plasma membranes specifically associated with matrix protein monolayers containing the Arg-Gly-Asp sequence recognized by integrin-type adhesion receptors. Experiments using fibronectin affinity chromatography to identify the synaptosomal receptors responsible for this interaction led to the purification of a 55 kDa Arg-Gly-Asp recognition protein that is labelled by antibodies against the alpha 5 beta 1 integrin.

SUBMITTER: Bahr BA 

PROVIDER: S-EPMC1130651 | biostudies-other | 1992 Jan

REPOSITORIES: biostudies-other