The arsonomethyl analogue of 3-phosphoglycerate.

ABSTRACT: 4-Arsono-2-hydroxybutanoic acid, the analogue of 3-phosphoglycerate in which -CH2-AsO3H2 replaces -O-PO3H2, was synthesized. It proved to be a substrate for phosphoglycerate kinase. Its Michaelis constant was only slightly higher than that of the natural substrate, but its catalytic constant was about 1300 times smaller.

SUBMITTER: Adams SR 

PROVIDER: S-EPMC1152110 | biostudies-other | 1983 Jul

REPOSITORIES: biostudies-other