Enhanced stability of the Na+-dependent amino acid-transport system after lymphocyte activation.

ABSTRACT: The Na+-dependent transport system for the amino acid proline in unstimulated lymphocytes decays with a half-life of about 4 h when protein synthesis is inhibited by cycloheximide, but the system in mitogen-activated lymphocytes is more stable. However, the early increase in activity of this transport system after mitogen addition is not due to a direct effect on its stability, but is a secondary effect requiring protein synthesis.

SUBMITTER: Borghetti AF 

PROVIDER: S-EPMC1161254 | biostudies-other | 1979 Jul

REPOSITORIES: biostudies-other