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Identification of an NAD(P)+-dependent 'malic' enzyme in small-intestinal-mucosal mitochondria.


ABSTRACT: An NAD(P)+-dependent 'malic' enzyme is shown to be present in mitochondria from small-intestinal mucosa. The intracellular location, activity and regulatory kinetic properties of the enzyme suggest that it participates in the major energy-producing pathway for net oxidation of glutamine-derived tricarboxylic acid-cycle intermediates.

SUBMITTER: Sauer LA 

PROVIDER: S-EPMC1161692 | biostudies-other | 1979 Oct

REPOSITORIES: biostudies-other