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GDP binding to brown-adipose-tissue mitochondria of diabetic--obese (db/db) mice. Decreased binding in both the obese and pre-obese states.


ABSTRACT: GDP binding to brown-adipose-tissue mitochondria from adult diabetic--obese (db/db) mice was significantly less than with lean siblings. Binding was also decreased in the mutant mice before obesity had begun to develop. Decreased GDP binding was found to result from a decrease in the number of binding sites.

SUBMITTER: Goodbody AE 

PROVIDER: S-EPMC1162842 | biostudies-other | 1981 Mar

REPOSITORIES: biostudies-other