Liposomal retention of a modified anti-inflammatory steroid.
Ontology highlight
ABSTRACT: In studies with synthetic lecithins, dipalmitoylphosphatidylcholine was found to be the preferred form for liposomal retention of cortisol esters at 37 degrees C. Cortisol palmitate was retained longer than cortisol octanoate, whereas unesterified cortisol escaped readily from liposomes. Such a liposome composition may allow the controlled release of modified anti-inflammatory agents, particularly when used for intra-articular administration.
SUBMITTER: Shaw IH
PROVIDER: S-EPMC1163990 | biostudies-other | 1976 Aug
REPOSITORIES: biostudies-other
ACCESS DATA
