A method for the determination of hyaluronate in the presence of other glycosaminoglycans and its application to human intervertebral disc.

ABSTRACT: A highly sensitive proteoglycan-binding assay was developed for the detection and determination of small amounts of hyaluronate. Application of this assay to human intervertebral-disc tissue showed that the radial distribution of hyaluronate closely followed the distribution of proteoglycans.

SUBMITTER: Hardingham TE 

PROVIDER: S-EPMC1164046 | biostudies-other | 1976 Oct

REPOSITORIES: biostudies-other