Nature of the interaction of chondroitin 4-sulphate and chondroitin sulphate-proteoglycan with collagen.
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ABSTRACT: The electrostatic interaction of chondroitin sulphate and the chondroitin sulphate-proteoglycan with collagen was studied by chromatography of the glycosaminoglycan and the proteoglycan on a collagen gel. The observed binding between the macromolecules increased with decreasing pH and ionic strength, and was significant under physiological conditions. A study of the interaction between chondroitin sulphate and a preparation of soluble collagen, with a partition-equilibrium technique, afforded similar results.
SUBMITTER: Obrink B
PROVIDER: S-EPMC1176559 | biostudies-other | 1971 Jan
REPOSITORIES: biostudies-other
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