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Effect of removal of calcium-activated adenosine triphosphatase from rat mast cells by treatment with sodium glycocholate.


ABSTRACT: Sodium glycocholate was shown to remove a Ca2+-activated adenosine triphosphatase from the external surface of the rat mast cell without causing lysis. Sensitized mast cells pretreated with sodium glycocholate showed a decrease in histamine-releasing capacity when triggered with antigen, Synacthen and ATP. Release induced by calcium ionophore A23187 was unaffected.

SUBMITTER: Cooper PH 

PROVIDER: S-EPMC1183810 | biostudies-other | 1977 Dec

REPOSITORIES: biostudies-other