Ontology highlight
ABSTRACT:
SUBMITTER: Kielbasa SM
PROVIDER: S-EPMC1261160 | biostudies-other | 2005
REPOSITORIES: biostudies-other
BMC bioinformatics 20050928
<h4>Background</h4>Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profiles complicate large scale analysis of transcription factor binding sites.<h4>Results</h4>We propose to identify and group similar profiles using two independent similarity measures: chi2 distances between position frequency matrices (PFMs) and correlation coefficients between position weight matrices (PWMs) scor ...[more]