Ontology highlight
ABSTRACT:
SUBMITTER: Watkins NE
PROVIDER: S-EPMC1277807 | biostudies-other | 2005
REPOSITORIES: biostudies-other
Nucleic acids research 20051101 19
Nearest-neighbor thermodynamic parameters of the 'universal pairing base' deoxyinosine were determined for the pairs I.C, I.A, I.T, I.G and I.I adjacent to G.C and A.T pairs. Ultraviolet absorbance melting curves were measured and non-linear regression performed on 84 oligonucleotide duplexes with 9 or 12 bp lengths. These data were combined with data for 13 inosine containing duplexes from the literature. Multiple linear regression was used to solve for the 32 nearest-neighbor unknowns. The par ...[more]