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Cloning and functional analysis of the gene encoding the 33- to 36-kilodalton outer membrane protein associated with carbapenem resistance in Acinetobacter baumannii.


ABSTRACT: We investigated a multiresistant strain of Acinetobacter baumannii isolated in our hospital. Analysis of the N-terminal peptide sequence of the outer membrane proteins (OMPs) purified from the strain allowed us to clone and sequence the nucleotides of the gene encoding the 33- to 36-kDa OMP associated with carbapenem resistance in A. baumannii.

SUBMITTER: del Mar Tomas M 

PROVIDER: S-EPMC1315955 | biostudies-other | 2005 Dec

REPOSITORIES: biostudies-other

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Cloning and functional analysis of the gene encoding the 33- to 36-kilodalton outer membrane protein associated with carbapenem resistance in Acinetobacter baumannii.

del Mar Tomás Maria M   Beceiro Alejandro A   Pérez Astrid A   Velasco David D   Moure Rita R   Villanueva Rosa R   Martínez-Beltrán Jesús J   Bou Germán G  

Antimicrobial agents and chemotherapy 20051201 12


We investigated a multiresistant strain of Acinetobacter baumannii isolated in our hospital. Analysis of the N-terminal peptide sequence of the outer membrane proteins (OMPs) purified from the strain allowed us to clone and sequence the nucleotides of the gene encoding the 33- to 36-kDa OMP associated with carbapenem resistance in A. baumannii. ...[more]