Ontology highlight
ABSTRACT:
SUBMITTER: Eid G
PROVIDER: S-EPMC173845 | biostudies-other | 1996 Mar
REPOSITORIES: biostudies-other
Infection and immunity 19960301 3
Antigenic variants of Anaplasma marginale major surface protein 2 (MSP-2), a target of protective immune responses, have been detected by use of copy-specific monoclonal antibodies reactive with some, but not all, organisms during acute rickettsemia. The presence of polymorphic msp-2 genes was confirmed by cloning and sequencing two gene copies, 11.2 and DF5, each of which encodes a full-length MSP-2 with a unique amino acid sequence. Transcription of msp-2 genes during acute rickettsemia was an ...[more]