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Simian AIDS type D serogroup 2 retrovirus: isolation of an infectious molecular clone and sequence analyses of its envelope glycoprotein gene and 3' long terminal repeat.


ABSTRACT: We describe the molecular cloning of a serogroup 2 simian retrovirus (SRV; D2/RHE/OR) and present the sequence of its envelope (env) glycoprotein gene and 3' long terminal repeat region. This report documents the first infectious molecular clone of a serogroup 2 SRV and provides env sequence verification of genetic diversity among serogroup 2 SRV isolates.

SUBMITTER: Marracci GH 

PROVIDER: S-EPMC188942 | biostudies-other | 1995 Apr

REPOSITORIES: biostudies-other

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Simian AIDS type D serogroup 2 retrovirus: isolation of an infectious molecular clone and sequence analyses of its envelope glycoprotein gene and 3' long terminal repeat.

Marracci G H GH   Kelley R D RD   Pilcher K Y KY   Crabtree L L   Shiigi S M SM   Avery N N   Leo G G   Webb M C MC   Hallick L M LM   Axthelm M K MK  

Journal of virology 19950401 4


We describe the molecular cloning of a serogroup 2 simian retrovirus (SRV; D2/RHE/OR) and present the sequence of its envelope (env) glycoprotein gene and 3' long terminal repeat region. This report documents the first infectious molecular clone of a serogroup 2 SRV and provides env sequence verification of genetic diversity among serogroup 2 SRV isolates. ...[more]