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The Salmonella typhimurium uracil-sensitive mutation use is in argU and encodes a minor arginine tRNA.

ABSTRACT: The use gene of Salmonella typhimurium was previously identified by a mutation conferring sensitivity to uracil in glucose minimal medium. The use gene was cloned and identified as an allele of argU encoding a tRNA for a minor arginine codon (CGG). The uracil-sensitive phenotype was shown to result from a base substitution in the anticodon stem of this tRNA.

SUBMITTER: Lu CD 

PROVIDER: S-EPMC204807 | biostudies-other | 1993 Jun

REPOSITORIES: biostudies-other

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The Salmonella typhimurium uracil-sensitive mutation use is in argU and encodes a minor arginine tRNA.

Lu C D CD   Abdelal A T AT  

Journal of bacteriology 19930601 12

The use gene of Salmonella typhimurium was previously identified by a mutation conferring sensitivity to uracil in glucose minimal medium. The use gene was cloned and identified as an allele of argU encoding a tRNA for a minor arginine codon (CGG). The uracil-sensitive phenotype was shown to result from a base substitution in the anticodon stem of this tRNA. ...[more]