Ontology highlight
ABSTRACT:
SUBMITTER: Ohara O
PROVIDER: S-EPMC2200107 | biostudies-other | 1993 Apr
REPOSITORIES: biostudies-other
Ohara O O Gahara Y Y Miyake T T Teraoka H H Kitamura T T
The Journal of cell biology 19930401 2
The existence of a neurofilament-deficient mutant of Japanese quail was recently documented (Yamasaki, H., C. Itakura, and M. Mizutani. 1991. Acta Neuropathol. 82:427-434), but the genetic events leading to the neurofilament deficiency have yet to be determined. Our molecular biological analyses revealed that the expression of neurofilament-L (NF-L) gene was specifically repressed in neurons of this mutant. To search for mutation(s) responsible for the shutdown of this gene expression, we cloned ...[more]