Ontology highlight
ABSTRACT:
SUBMITTER: McKune K
PROVIDER: S-EPMC230944 | biostudies-other | 1995 Dec
REPOSITORIES: biostudies-other
Molecular and cellular biology 19951201 12
To assess functional relatedness of individual components of the eukaryotic transcription apparatus, three human subunits (hsRPB5, hsRPB8, and hsRPB10) were tested for their ability to support yeast cell growth in the absence of their essential yeast homologs. Two of the three subunits, hsRPB8 and hsRPB10, supported normal yeast cell growth at moderate temperatures. A fourth human subunit, hsRPB9, is a homolog of the nonessential yeast subunit RPB9. Yeast cells lacking RPB9 are unable to grow at ...[more]