Ontology highlight
ABSTRACT:
SUBMITTER: Zhong H
PROVIDER: S-EPMC3193492 | biostudies-other | 2011 Jul
REPOSITORIES: biostudies-other
Zhong Hanbing H Wang Danyang D Wang Nan N Rios Yesenia Y Huang Haigen H Li Song S Wu Xinrong X Lin Shuo S
Cell research 20110322 7
Blood vessels normally maintain stereotyped lumen diameters and their stable structures are crucial for vascular function. However, very little is known about the molecular mechanisms controlling the maintenance of vessel diameters and the integrity of endothelial cells. We investigated this issue in zebrafish embryos by a chemical genetics approach. Small molecule libraries were screened using live Tg(kdrl:GRCFP)(zn1) transgenic embryos in which endothelial cells are specifically labeled with G ...[more]