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Long-term treatment of metastatic colorectal cancer with panitumumab.


ABSTRACT: Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. More than 30% patients present with metastases at diagnoses and will require systemic chemotherapy. In recent years many anti-EGFR targets have been developed. Among them, panitumumab, a fully human IgG2 monoclonal antibody has shown important benefits in the treatment of this disease.

SUBMITTER: Lopez-Gomez M 

PROVIDER: S-EPMC3296490 | biostudies-other | 2012

REPOSITORIES: biostudies-other

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Long-term treatment of metastatic colorectal cancer with panitumumab.

López-Gómez Miriam M   Merino María M   Casado Enrique E  

Clinical Medicine Insights. Oncology 20120228


Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. More than 30% patients present with metastases at diagnoses and will require systemic chemotherapy. In recent years many anti-EGFR targets have been developed. Among them, panitumumab, a fully human IgG2 monoclonal antibody has shown important benefits in the treatment of this disease. ...[more]

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