Ontology highlight
ABSTRACT:
SUBMITTER: Harding FA
PROVIDER: S-EPMC332511 | biostudies-other | 1990 Nov
REPOSITORIES: biostudies-other
Nucleic acids research 19901101 21
Immunoglobulin heavy chain genes in Raja erinacea (little skate) are organized in clusters consisting of VH, DH, JH segments and CH exons (1). An immunoglobulin heavy chain mu-like isotype that exhibits 61-91% nucleotide sequence identity in coding segments to the Heterodontus francisci (horned shark) mu-type immunoglobulin is described. The overall length of the mu-type clusters is approximately 16 kb; transmembrane exons (TM1 and TM2) are located 3 to CH exon 4 (CH4). In three of four TM-conta ...[more]