Dataset Information
Total synthesis of (-)-irciniastatin B and structural confirmation via chemical conversion to (+)-irciniastatin A (psymberin).
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ABSTRACT:
SUBMITTER: An C
PROVIDER: S-EPMC3438514 | biostudies-other | 2012 Sep
REPOSITORIES: biostudies-other
Publications
Total synthesis of (-)-irciniastatin B and structural confirmation via chemical conversion to (+)-irciniastatin A (psymberin).
Organic letters 20120814 17
The total synthesis and structural confirmation of the marine sponge cytotoxin (-)-irciniastatin B has been achieved via a unified strategy employing a late-stage, selective deprotection/oxidation sequence that provides access to both (+)-irciniastatin A (psymberin) and (-)-irciniastatin B. ...[more]