Ontology highlight
ABSTRACT:
SUBMITTER: Leao RN
PROVIDER: S-EPMC3483451 | biostudies-other | 2012 Nov
REPOSITORIES: biostudies-other
Leão Richardson N RN Mikulovic Sanja S Leão Katarina E KE Munguba Hermany H Gezelius Henrik H Enjin Anders A Patra Kalicharan K Eriksson Anders A Loew Leslie M LM Tort Adriano B L AB Kullander Klas K
Nature neuroscience 20121007 11
The vast diversity of GABAergic interneurons is believed to endow hippocampal microcircuits with the required flexibility for memory encoding and retrieval. However, dissection of the functional roles of defined interneuron types has been hampered by the lack of cell-specific tools. We identified a precise molecular marker for a population of hippocampal GABAergic interneurons known as oriens lacunosum-moleculare (OLM) cells. By combining transgenic mice and optogenetic tools, we found that OLM ...[more]