Re-scan confocal microscopy: scanning twice for better resolution.

ABSTRACT: We present a new super-resolution technique, Re-scan Confocal Microscopy (RCM), based on standard confocal microscopy extended with an optical (re-scanning) unit that projects the image directly on a CCD-camera. This new microscope has improved lateral resolution and strongly improved sensitivity while maintaining the sectioning capability of a standard confocal microscope. This simple technology is typically useful for biological applications where the combination high-resolution and high-sensitivity is required.

SUBMITTER: De Luca GM 

PROVIDER: S-EPMC3829557 | biostudies-other | 2013

REPOSITORIES: biostudies-other