Metabolites from intestinal microbes shape Treg.

ABSTRACT: Intestinal bacterial metabolites are an important communication tool between the host immune system and the commensal microbiota to establish mutualism. In a recent paper published in Science, Wendy Garrett and her colleagues report an exciting role of the three most abundant microbial-derived short-chain fatty acids (SCFA), acetic acid, propionic acid and butyric acid, in colonic regulatory T cell (cTreg) homeostasis.

SUBMITTER: Geuking MB 

PROVIDER: S-EPMC3847568 | biostudies-other | 2013 Dec

REPOSITORIES: biostudies-other