Unknown

Dataset Information

0

The influence of fasting insulin level in post-gestational diabetes mellitus women receiving low-glycaemic-index diets.


ABSTRACT: Post-gestational diabetes mellitus (GDM) women are recommended weight loss to manage increased cardio-metabolic risks. We investigated the effects of lowering diet glycaemic index (GI) on fasting blood glucose (FBG), serum lipids, body weight and composition of post-GDM women with varying fasting insulin levels (INS). Seventy-seven Asian, non-diabetic women with previous GDM (aged 20-40 years, mean BMI: 26.4±4.6 kg m(-2)) were recruited. At baseline, 20 subjects with INS <2 μIU ml(-1) and 18 with INS 2 μIU ml(-1) received conventional dietary recommendations (CHDR) only. CHDR emphasised energy and fat intake restriction and encouraged increase in dietary fibre intakes. Twenty-four subjects with INS <2 μIU ml(-1) and 15 with INS 2 μIU ml(-1), in addition to CHDR, received low-GI education (LGI). Changes in FBG, serum lipids, body weight and body composition were evaluated. Subjects with INS <2 μIU ml(-1) had similar outcomes with both diets. After 1 year, subjects with INS 2 μIU ml(-1) who received LGI education had reductions in FBG and triglycerides. Subjects who received CHDR observed increase in both FBG and triglycerides (P<0.05). Among all subjects, diet GI was lower and dietary fibre intakes were higher in LGI compared with CHDR subjects (all P<0.05). Thus, in Asian post-GDM women with normal/higher INS, adding low-GI education to CHDR improved management of FBG and triglycerides.

SUBMITTER: Ghani RA 

PROVIDER: S-EPMC3940829 | biostudies-other | 2014

REPOSITORIES: biostudies-other

Similar Datasets

| S-EPMC7100550 | biostudies-literature
| S-EPMC5849787 | biostudies-other
| S-EPMC8634573 | biostudies-literature
| S-EPMC9374239 | biostudies-literature
| S-EPMC9681895 | biostudies-literature
| S-EPMC10005728 | biostudies-literature
| S-EPMC4844174 | biostudies-literature
| S-EPMC7685611 | biostudies-literature
| S-EPMC9020000 | biostudies-literature
| S-EPMC6529712 | biostudies-literature