Study of the effect of distance and misalignment between magnetically coupled coils for wireless power transfer in intraocular pressure measurement.
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ABSTRACT:
SUBMITTER: Rendon-Nava AE
PROVIDER: S-EPMC4109074 | biostudies-other | 2014
REPOSITORIES: biostudies-other
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Project description:An important aspect of eye health in humans and animal models of human diseases is intraocular pressure (IOP). IOP is typically measured by hand with a tonometer, so data are sparse and sporadic and round-the-clock variations are not well characterized. Here we present a novel system for continuous wireless IOP and temperature measurement in small animals. The system consists of a cannula implanted in the anterior chamber of the eye connected to pressure sensing electronics that can be worn by rats or implanted in larger mammals. The system can record IOP with 0.3 mmHg accuracy and negligible drift at a rate of 0.25 Hz for 1-2 months on a regulated battery or indefinitely at rates up to 250 Hz via RF energy harvesting. Chronic recordings from conscious rats showed that IOP follows a diurnal rhythm, averaging 16.5 mmHg during the day and 21.7 mmHg at night, and that the IOP rhythm lags a diurnal rhythm in body temperature by 2.1 h. IOP and body temperature fluctuations were positively correlated from moment-to-moment as well. This technology allows researchers to monitor for the first time the precise IOP history of rat eyes, a popular model for glaucoma studies.
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Project description:Earlier work on RF metasurfaces for preclinical MRI has targeted applications such as whole-body imaging and dual-frequency coils. In these studies, a nonresonant loop was used to induce currents into a metasurface that was operated as a passive inductively powered resonator. However, as we show in this study, the strategy of using a resonant metasurface reduces the impact of the loop on the global performance of the assembled coil. To mitigate this deficiency, we developed a new approach that relies on the combination of a commercial surface coil and a coupled-wire structure operated away from its resonance. This strategy enables the extension of the sensitive volume of the surface coil while maintaining its local high sensitivity without any hardware modification. A wireless coil based on a two parallel coupled-wire structure was designed and electromagnetic field simulations were carried out with different levels of matching and coupling between both components of the coil. For experimental characterization, a prototype was built and tested at two frequencies, 300 MHz for 1 H and 282.6 MHz for 19 F at 7 T. Phantom and in vivo MRI experiments were conducted in different configurations to study signal and noise figures of the structure. The results showed that the proposed strategy improves the overall sensitive volume while simultaneously maintaining a high signal-to-noise ratio (SNR). Metasurfaces based on coupled wires are therefore shown here as promising and versatile elements in the MRI RF chain, as they allow customized adjustment of the sensitive volume as a function of SNR yield. In addition, they can be easily adapted to different Larmor frequencies without loss of performance.
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Project description:This paper proposes an on-line method for foreign object detection in a double DD coil system. The foreign object is detected by real-time measurement of the mutual inductance between the transfer pads. Measurement of the mutual inductance between coils can be performed at the start, during initialisation, or during the wireless power transfer. The coils in the double DD coil structure can be used separately; one coil can be used for power transfer and the other can be used for the mutual inductance measurement. The mutual inductance measurement is based on the voltage measurement across the open circuit receiver coil. The measured value of mutual inductance between the transmitter and the receiver pad can be used in a control algorithm and in a foreign object detection algorithm. Additionally, a 2DDq coil structure can be used as a replacement for the double DD coil structure, which increases the power transfer density. The DD coils in the double DD coil structure can also be driven using two phase-shifted voltages, which enables better location and detection of foreign objects. The method also helps to differentiate the mutual inductance change due to the distance change from the mutual inductance change due to the presence of a foreign object.
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