Zwitteration: coating surfaces with zwitterionic functionality to reduce nonspecific adsorption.

ABSTRACT: Coating surfaces with thin or thick films of zwitterionic material is an effective way to reduce or eliminate nonspecific adsorption to the solid/liquid interface. This review tracks the various approaches to zwitteration, such as monolayer assemblies and polymeric brush coatings, on micro- to macroscopic surfaces. A critical summary of the mechanisms responsible for antifouling shows how zwitterions are ideally suited to this task.

SUBMITTER: Schlenoff JB 

PROVIDER: S-EPMC4140545 | biostudies-other | 2014 Aug

REPOSITORIES: biostudies-other