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Detecting "different": Pyrin senses modified GTPases.


ABSTRACT: Pathogenic bacteria secrete effector proteins that target host cell Rho GTPases to manipulate the actin cytoskeleton. A recent study in Nature identifies the Pyrin inflammasome as a sensor of this pathogenic process.

SUBMITTER: de Zoete MR 

PROVIDER: S-EPMC4220150 | biostudies-other | 2014 Nov

REPOSITORIES: biostudies-other

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