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Producing GM-CSF: a unique T helper subset?

ABSTRACT: GM-CSF-producing helper T cells have previously been identified to serve a nonredundant function in the initiation of autoimmune inflammation. An article by Sheng et al. recently published by Cell Research now suggests that the differentiation program of GM-CSF-producing cells from naïve CD4 T cells is distinct from that of Th1 and Th17 cells, and is regulated by the IL-7-STAT5 axis.

SUBMITTER: Herndler-Brandstetter D

PROVIDER: S-EPMC4260353 | biostudies-other | 2014 Dec

REPOSITORIES: biostudies-other

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