Unknown

Dataset Information

0

The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications.

ABSTRACT: Pinocembrin is a natural flavonoid compound extracted from honey, propolis, ginger roots, wild marjoram, and other plants. In preclinical studies, it has shown anti-inflammatory and neuroprotective effects as well as the ability to reduce reactive oxygen species, protect the blood-brain barrier, modulate mitochondrial function, and regulate apoptosis. Considering these pharmaceutical characteristics, pinocembrin has potential as a drug to treat ischemic stroke and other clinical conditions. In this review, we summarize its pharmacologic characteristics and discuss its mechanisms of action and potential therapeutic applications.

SUBMITTER: Lan X 

PROVIDER: S-EPMC4561606 | biostudies-other | 2016 Apr

REPOSITORIES: biostudies-other

Json Xml
altmetric image

Publications

The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications.

Lan Xi X   Wang Wenzhu W   Li Qiang Q   Wang Jian J  

Molecular neurobiology 20150307 3

Pinocembrin is a natural flavonoid compound extracted from honey, propolis, ginger roots, wild marjoram, and other plants. In preclinical studies, it has shown anti-inflammatory and neuroprotective effects as well as the ability to reduce reactive oxygen species, protect the blood-brain barrier, modulate mitochondrial function, and regulate apoptosis. Considering these pharmaceutical characteristics, pinocembrin has potential as a drug to treat ischemic stroke and other clinical conditions. In t  ...[more]

Similar Datasets

Unknown Molecular basis of ? thalassemia and potential therapeutic targets.
| S-EPMC5738298 | biostudies-literature
Unknown Circular RNAs: Potential Applications as Therapeutic Targets and Biomarkers in Breast Cancer.
| S-EPMC7838774 | biostudies-literature
Unknown IDH mutation in glioma: molecular mechanisms and potential therapeutic targets.
| S-EPMC7250901 | biostudies-literature
Unknown Molecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targets.
| S-EPMC6657312 | biostudies-literature
Transcriptomics Molecular expression profile reveals potential biomarkers and therapeutic targets incanine endometrial lesions
2015-07-11 | E-GEOD-69481 | biostudies-arrayexpress
Unknown Ginsenoside Rg3: Potential Molecular Targets and Therapeutic Indication in Metastatic Breast Cancer.
| S-EPMC6473622 | biostudies-literature
Unknown Molecular features of hepatosplenic T-cell lymphoma unravels potential novel therapeutic targets.
| S-EPMC3779008 | biostudies-literature
Unknown Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets.
| S-EPMC8585639 | biostudies-literature
Unknown Potential therapeutic molecular targets for blood-brain barrier disruption after subarachnoid hemorrhage.
| S-EPMC6425837 | biostudies-literature
Unknown Exploring the molecular targets of dietary flavonoid fisetin in cancer.
| S-EPMC5067175 | biostudies-literature