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Therapeutic potential of interleukin-27 against cancers in preclinical mouse models.

ABSTRACT: Since we first reported the antitumor efficacy of IL-27 in 2004, accumulating evidence obtained by several groups using a variety of preclinical mouse models indicates that IL-27 possesses potent antitumor activity against various types of tumors through multiple mechanisms depending on the characteristics of individual tumors without apparent adverse effects.

SUBMITTER: Mizoguchi I 

PROVIDER: S-EPMC4589049 | biostudies-other | 2015 Oct

REPOSITORIES: biostudies-other

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