Ontology highlight
ABSTRACT:
SUBMITTER: Basit A
PROVIDER: S-EPMC4744830 | biostudies-other | 2016
REPOSITORIES: biostudies-other
Metabolomics : Official journal of the Metabolomic Society 20160208
We describe a simple method for the detection of low intensity lipid signals in complex tissue samples, based on a combination of liquid chromatography/mass spectrometry and ion mobility mass spectrometry. The method relies on visual and software-assisted analysis of overlapped mobilograms (diagrams of mass-to-charge ratio, <i>m/z</i>, <i>vs</i> drift time, DT) and was successfully applied in untargeted lipidomics analyses of mouse brain tissue to detect relatively small variations in a scarce c ...[more]