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Carotid Baroreceptor Stimulation and Arteriovenous Shunts for Resistant Hypertension.


ABSTRACT: Pharmacologic therapy for hypertension is effective for the majority of patients with hypertension, but there is a subset of the population with treatment-resistant hypertension who cannot achieve their blood pressure goal despite taking multiple medications. Since these patients are at increased risk of cardiovascular disease and end-organ damage, additional therapies must be considered. This review discusses several novel interventional therapies-including baroreflex activation therapy, baroreceptor stenting, and creation of an arteriovenous shunt-that may provide alternative options for blood pressure control in those with treatment-resistant hypertension. All of these therapies remain investigational, and each has its own strengths and weaknesses that will be critical to assess as they come to market.

SUBMITTER: Paivanas N 

PROVIDER: S-EPMC4814008 | biostudies-other | 2015 Oct-Dec

REPOSITORIES: biostudies-other

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Carotid Baroreceptor Stimulation and Arteriovenous Shunts for Resistant Hypertension.

Paivanas Nicholas N   Bisognano John D JD   Gassler John P JP  

Methodist DeBakey cardiovascular journal 20151001 4


Pharmacologic therapy for hypertension is effective for the majority of patients with hypertension, but there is a subset of the population with treatment-resistant hypertension who cannot achieve their blood pressure goal despite taking multiple medications. Since these patients are at increased risk of cardiovascular disease and end-organ damage, additional therapies must be considered. This review discusses several novel interventional therapies-including baroreflex activation therapy, barore  ...[more]