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Genome-wide DNA methylation profiling in triple-negative breast cancer reveals epigenetic signatures with important clinical value.

ABSTRACT: Analysis of cancer methylomes has dramatically changed our concept of the potential of diagnostic and prognostic methylation biomarkers in disease stratification. Through whole-genome methylation capture sequencing of triple-negative breast cancers (TNBCs) we recently identified differentially methylated regions with diagnostic and prognostic value that promise to stratify TNBCs for more personalized management.

SUBMITTER: Stirzaker C 

PROVIDER: S-EPMC4845196 | biostudies-other | 2016 Jan

REPOSITORIES: biostudies-other

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