C-Abl forces YAP to switch sides.

ABSTRACT: Cancer research has been significantly accelerated by viewing cancer as a functional collision between 2 dichotomous sets of genes: oncogenes and tumor suppressors. Signaling pathways turn oncogenes and tumor suppressors on and off to dictate cell fate decisions. We contend that signaling also dictates opposing behaviors of a given effector.

SUBMITTER: Keshet R 

PROVIDER: S-EPMC4905508 | biostudies-other | 2015 Jul-Sep

REPOSITORIES: biostudies-other