Suv39h1 links the SUMO pathway to constitutive heterochromatin.

ABSTRACT: The Suv39h lysine methyltransferases, known as key enzymes responsible for histone H3 lysine 9 methylation, are critical for heterochromatin protein 1 enrichment at constitutive heterochromatin. Our recent findings reveal a new role for the Suv39h1 paralog that links it to SUMO pathway function at constitutive heterochromatin.

SUBMITTER: Maison C 

PROVIDER: S-EPMC5160415 | biostudies-other | 2016

REPOSITORIES: biostudies-other