Rearranged subtelomeric rRNA genes in Giardia duodenalis.

ABSTRACT: Giardia duodenalis has linear chromosomes capped with typical eukaryotic repeats [(TAGGG)n], subtelomeric rRNA genes, and telomere gene units. The absence of two closely associated NotI sites in the large-subunit rRNA gene was used as an indicator in hybridizations of one- and two-dimensional NotI-cleaved Giardia chromosome separations that some chromosomes carry only rearranged and, by deduction, nonfunctional rRNA genes.

SUBMITTER: Upcroft JA 

PROVIDER: S-EPMC549325 | biostudies-other | 2005 Feb

REPOSITORIES: biostudies-other