Co-evolution techniques are reshaping the way we do structural bioinformatics.

ABSTRACT: Co-evolution techniques were originally conceived to assist in protein structure prediction by inferring pairs of residues that share spatial proximity. However, the functional relationships that can be extrapolated from co-evolution have also proven to be useful in a wide array of structural bioinformatics applications. These techniques are a powerful way to extract structural and functional information in a sequence-rich world.

SUBMITTER: de Oliveira S 

PROVIDER: S-EPMC5531156 | biostudies-other | 2017

REPOSITORIES: biostudies-other