Why could a woman have three Trisomy 21 pregnancies? - a case report.

ABSTRACT: Mosaicism, an important cause for recurrent T21, should be suspected in families with more than one affected child wishing to receive prenatal counseling. Fluorescence in-situ hybridization analysis in a large number of cells and in different tissue samples is critical for detecting low-level mosaicism and is a key prognostic factor.

SUBMITTER: Magalhaes M 

PROVIDER: S-EPMC5538204 | biostudies-other | 2017 Aug

REPOSITORIES: biostudies-other