Unknown

Dataset Information

0

Triglycerides and Open Angle Glaucoma - A Meta-analysis with meta-regression.

ABSTRACT: Although intraocular pressure is the main the risk factor for the development of glaucoma, other risk factors such as vascular dysfunction might play an additional pathogenic role. Hypertriglyceridemia, which may lead to vascular dysfunction, has been implicated in the development of glaucoma. The objective of this meta-analysis was to investigate the association of triglyceride levels with the risk of glaucoma in case-control studies. Seventeen case-control studies were included investigating the difference in triglyceride levels in patients with glaucoma (N?=?1 391) compared to subjects without glaucoma (N?=?25 575). In random effects meta-analysis, the pooled mean triglyceride level across all studies and patients with and without glaucoma was 132.9?mg/dL (95%CI: 124.0-141.7). Patients with glaucoma had significantly higher mean triglyceride levels than patients without glaucoma (absolute difference?=?14.2?mg/dL, 95%CI: 5.8-22.5, p?

SUBMITTER: Pertl L 

PROVIDER: S-EPMC5552857 | biostudies-other | 2017 Aug

REPOSITORIES: biostudies-other

Json Xml
altmetric image

Publications

Triglycerides and Open Angle Glaucoma - A Meta-analysis with meta-regression.

Pertl Laura L   Mossböck Georg G   Wedrich Andreas A   Weger Martin M   Königsbrügge Oliver O   Silbernagel Günther G   Posch Florian F  

Scientific reports 20170810 1

Although intraocular pressure is the main the risk factor for the development of glaucoma, other risk factors such as vascular dysfunction might play an additional pathogenic role. Hypertriglyceridemia, which may lead to vascular dysfunction, has been implicated in the development of glaucoma. The objective of this meta-analysis was to investigate the association of triglyceride levels with the risk of glaucoma in case-control studies. Seventeen case-control studies were included investigating t  ...[more]