On the fast track to organizer gene expression.

ABSTRACT: Many embryonic species are initially transcriptionally quiescent after fertilization. In this issue of Developmental Cell, Blythe et al. reveal that beta-catenin acts very early in Xenopus development to specifically modify the chromatin of organizer genes, poising them for rapid activation when transcription begins.

SUBMITTER: Kimelman D 

PROVIDER: S-EPMC5568668 | biostudies-other | 2010 Aug

REPOSITORIES: biostudies-other