Ontology highlight
ABSTRACT:
SUBMITTER: Furlan A
PROVIDER: S-EPMC6013038 | biostudies-other | 2017 Jul
REPOSITORIES: biostudies-other
Science (New York, N.Y.) 20170701 6346
Adrenaline is a fundamental circulating hormone for bodily responses to internal and external stressors. Chromaffin cells of the adrenal medulla (AM) represent the main neuroendocrine adrenergic component and are believed to differentiate from neural crest cells. We demonstrate that large numbers of chromaffin cells arise from peripheral glial stem cells, termed Schwann cell precursors (SCPs). SCPs migrate along the visceral motor nerve to the vicinity of the forming adrenal gland, where they de ...[more]