Chronotype and social jetlag influence human circadian clock gene expression.

ABSTRACT: We examined the relationships between chronotype or social jetlag and clock gene expression. Twenty-four young men [Chronotype: morningness, n?=?8; intermediate, n?=?8, eveningness, n?=?8], aged 27?±?2 years old (mean?±?SE), completed two trials in a randomized order: (1) a Friday trial and (2) a Monday trial. In both trials, hair follicle cells were collected to evaluate the expression of clock genes over a 24-hour period at 4-hour intervals. There was a significant main effect of time on the expression of NR1D1, NR1D2, and PER3 (P?

SUBMITTER: Takahashi M 

PROVIDER: S-EPMC6033857 | biostudies-other | 2018 Jul

REPOSITORIES: biostudies-other